BIO ONE

BIO ONE je zasnovan z mislijo na prilagodljivost, kar uporabnikom omogoča, da dodajo katerikoli biomaterial in ga uporabijo za tiskanje. Robustna in zanesljiva konstrukcija, dovolj majhna, da se prilega v vaš laminar ali na delovno mizo, naredi BIO ONE idealnega za tiskanje kapljic, nizov kapljic in mrež, kar omogoča enostavno proizvodnjo organoidov, sferoidov in tkivnih konstrukcij, ki pospešijo vaše raziskovanje. To se doseže preko DNA Studio Core, kjer lahko enostavno prilagodimo tiskalne parametre, kot so volumen retrakcije in hitrost iztiskanja. V kombinaciji s hladilnimi zmogljivostmi tiskalne glave in ogrevano tiskovno ploščo se povečuje prilagodljivost sistema pri uporabi biomaterialov.

Kolagen
Hladilna tiskalna glava BIO ONE, integrirana v biotiskalnik, igra ključno vlogo pri ohranjanju strukturne integritete kolagena med tiskanjem. Tehnologija hlajenja učinkovito preprečuje denaturacijo ali degradacijo kolagena. CELLINK ponuja več vrst kolagena, kar raziskovalcem omogoča prilagodljive možnosti za različne aplikacije z omejeno variabilnostjo med serijami.

Matrigel®
Matrigel® se danes pogosto uporablja v celičnih študijah. Njegova gelasta narava, bogata z rastnimi dejavniki in bioaktivnimi komponentami, zahteva natančno ravnanje med biotiskanjem. Integracija hladilne tiskalne glave BIO ONE preprečuje geliranje in minimizira tveganje zamašitve, kar rezultira v doslednih in ponovljivih tiskanih konstrukcijah z visoko tiskovno natančnostjo.

Prilagojeni materiali
BIO ONE je zasnovan za tiskanje z katerimkoli biomaterialom po vaši izbiri. Pri uporabi prilagojenega materiala – bodisi pri razvoju lastnega ali nakupu pri drugem dobavitelju – je pomembno upoštevati lastnosti BIO ONE. Namreč, temperaturna območja tiskalne glave od 0 °C do sobne temperatre in temperaturna območja tiskovne plošče od soben temperature do 65 °C igrajo ključno vlogo pri določanju združljivosti materialov. Če želite izvedeti, ali bo vaš material dobro deloval z BIO ONE, nas kontaktirajte

Feature	Description	Applications
Cooling capabilities	Rapidly cools the BIO ONE printhead down to 0 °C and maintains the temperature throughout the print. Ensures temperature stability from start to finish.	Tissue Engineering: Enables the creation of 3D tissue models for studying regenerative properties, wound healing, and developing in vitro alternatives to animal testing.
Material flexibility	Open material platform allows users to load and dispense any material, including temperature-sensitive materials like collagen.	Material Science: Ideal for developing and testing new biomaterials, including bioinks, soft robotics, and smart materials by fine-tuning parameters for most materials.
Precision extrusion	High-precision mechanical extrusion with a 0.1 μL volume step enables total control over the print.	Drug Discovery: Provides high throughput with up to 384-well plates, enabling easy testing of drug candidates and investigating drug delivery in reproducible in vitro models.
Heated printbed	Built-in printbed heating from RT to 65 °C enhances construct stability and cell viability for heat-responsive materials through thermal crosslinking.	Tissue Engineering: Useful for building complex tissue structures where temperature control is key to maintaining cell viability.
Maximized reproducibility	Ensures highly reproducible structures with minimal variation and reduced human error, allowing protocols to be saved to the software.	Material Science: Supports reliable testing of new materials by ensuring consistency across multiple print runs.
DNA Studio Core	DNA Studio Core powers the BIO ONE for ease-of-use, making it simpler to enter the world of 3D cell culture.	Tissue Engineering: Simplifies the bioprinting process, making it easier to start developing complex tissue models for regenerative medicine, wound healing, and more. Drug Discovery: Streamlines research into drug interactions within cell cultures, saving time and improving precision.